Oropouche Virus Infection and Pathogenesis Are Restricted by MAVS, IRF-3, IRF-7, and Type I Interferon Signaling Pathways in Nonmyeloid Cells

Oropouche virus (OROV) is a member of the Orthobunyavirus genus in the Bunyaviridae family and a prominent cause of insect-transmitted viral disease in Central and South America. Despite its clinical relevance, little is known about OROV pathogenesis. To define the host defense pathways that control...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Proenca-Modena, Jose Luiz, Sesti-Costa, Renata, Pinto, Amelia K., Richner, Justin M., Lazear, Helen M., Lucas, Tiffany, Hyde, Jennifer L., Diamond, Michael S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403474/
https://ncbi.nlm.nih.gov/pubmed/25717109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00077-15
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