Oncogenic Human T-Cell Lymphotropic Virus Type 1 Tax Suppression of Primary Innate Immune Signaling Pathways

Human T-cell lymphotropic virus type I (HTLV-1) is an oncogenic retrovirus considered to be the etiological agent of adult T-cell leukemia (ATL). The viral transactivator Tax is regarded as the oncoprotein responsible for contributing toward the transformation process. Here, we demonstrate that Tax...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Hyun, Jinhee, Ramos, Juan Carlos, Toomey, Ngoc, Balachandran, Siddharth, Lavorgna, Alfonso, Harhaj, Edward, Barber, Glen N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403453/
https://ncbi.nlm.nih.gov/pubmed/25694597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02493-14
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