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Is there a role for ubiquitin or SUMO in human T-cell leukemia virus type 2 Tax-induced NF-κB activation?

It is well established that the human T-cell leukemia virus type 1-encoded oncoprotein Tax (Tax1) undergoes polyubiquitination as part of its mechanism to persistently activate NF-κB. However, it remains unclear whether Tax2 encoded by the closely related human T-cell leukemia virus type 2 utilizes...

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Detalhes bibliográficos
Main Authors: Lavorgna, Alfonso, Harhaj, Edward W
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665948/
https://ncbi.nlm.nih.gov/pubmed/23730325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fvl.13.1
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