A Critical Role for IL-17RB Signaling in HTLV-1 Tax-Induced NF-κB Activation and T-Cell Transformation

Human T-cell leukemia virus type 1 (HTLV-1) infection is linked to the development of adult T-cell leukemia (ATL) and the neuroinflammatory disease HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). The HTLV-1 Tax protein functions as a potent viral oncogene that constitutively act...

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Main Authors: Lavorgna, Alfonso, Matsuoka, Masao, Harhaj, Edward William
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207800/
https://ncbi.nlm.nih.gov/pubmed/25340344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004418
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