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The Susceptibility of Primate Lentiviruses to Nucleosides and Vpx during Infection of Dendritic Cells Is Regulated by CA

The block toward human immunodeficiency virus type 1 (HIV-1) infection of dendritic cells (DCs) can be relieved by Vpx (viral protein X), which degrades sterile alpha motif-hydroxylase domain 1 (SAMHD1) or by exogenously added deoxynucleosides (dNs), lending support to the hypothesis that SAMHD1 act...

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Publicat a:J Virol
Autors principals: Barateau, Véronique, Nguyen, Xuan-Nhi, Bourguillault, Fanny, Berger, Grégory, Cordeil, Stéphanie, Cimarelli, Andrea
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403438/
https://ncbi.nlm.nih.gov/pubmed/25609804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03315-14
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