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Control of Hepatitis C Virus Replication in Mouse Liver-Derived Cells by MAVS-Dependent Production of Type I and Type III Interferons

Hepatitis C virus (HCV) efficiently infects only humans and chimpanzees. Although the detailed mechanisms responsible for this narrow species tropism remain elusive, recent evidence has shown that murine innate immune responses efficiently suppress HCV replication. Therefore, poor adaptation of HCV...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Anggakusuma, Frentzen, Anne, Gürlevik, Engin, Yuan, Qinggong, Steinmann, Eike, Ott, Michael, Staeheli, Peter, Schmid-Burgk, Jonathan, Schmidt, Tobias, Hornung, Veit, Kuehnel, Florian, Pietschmann, Thomas
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403415/
https://ncbi.nlm.nih.gov/pubmed/25609814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03129-14
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