Control of Hepatitis C Virus Replication in Mouse Liver-Derived Cells by MAVS-Dependent Production of Type I and Type III Interferons

Hepatitis C virus (HCV) efficiently infects only humans and chimpanzees. Although the detailed mechanisms responsible for this narrow species tropism remain elusive, recent evidence has shown that murine innate immune responses efficiently suppress HCV replication. Therefore, poor adaptation of HCV...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Anggakusuma, Frentzen, Anne, Gürlevik, Engin, Yuan, Qinggong, Steinmann, Eike, Ott, Michael, Staeheli, Peter, Schmid-Burgk, Jonathan, Schmidt, Tobias, Hornung, Veit, Kuehnel, Florian, Pietschmann, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Cellular Response to Infection
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403415/
https://ncbi.nlm.nih.gov/pubmed/25609814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03129-14
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