Control of Hepatitis C Virus Replication in Mouse Liver-Derived Cells by MAVS-Dependent Production of Type I and Type III Interferons

Hepatitis C virus (HCV) efficiently infects only humans and chimpanzees. Although the detailed mechanisms responsible for this narrow species tropism remain elusive, recent evidence has shown that murine innate immune responses efficiently suppress HCV replication. Therefore, poor adaptation of HCV...

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Vydáno v:J Virol
Hlavní autoři: Anggakusuma, Frentzen, Anne, Gürlevik, Engin, Yuan, Qinggong, Steinmann, Eike, Ott, Michael, Staeheli, Peter, Schmid-Burgk, Jonathan, Schmidt, Tobias, Hornung, Veit, Kuehnel, Florian, Pietschmann, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Cellular Response to Infection
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403415/
https://ncbi.nlm.nih.gov/pubmed/25609814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03129-14
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