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Requirement for Fc Effector Mechanisms in the APOBEC3/Rfv3-Dependent Neutralizing Antibody Response

Antiretroviral neutralizing antibody (NAb) responses are often evaluated in the absence of Fc-dependent immune effectors. In murine Friend retrovirus infection, Apobec3/Rfv3 promotes a potent polyclonal NAb response. Here, we show that the Apobec3/Rfv3-dependent NAb response correlated with virus-sp...

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Publicat a:J Virol
Autors principals: Halemano, Kalani, Barrett, Bradley S., Heilman, Karl J., Morrison, Thomas E., Santiago, Mario L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403405/
https://ncbi.nlm.nih.gov/pubmed/25589647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03399-14
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