Phenotypic and Functional Characterization of Herpes Simplex Virus Glycoprotein B Epitope-Specific Effector and Memory CD8(+) T Cells from Symptomatic and Asymptomatic Individuals with Ocular Herpes

Herpes simplex virus 1 (HSV-1) glycoprotein B (gB)-specific CD8(+) T cells protect mice from herpes infection and disease. However, whether and which HSV-1 gB-specific CD8(+) T cells play a key role in the “natural” protection seen in HSV-1-seropositive healthy asymptomatic (ASYMP) individuals (who...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Khan, Arif A., Srivastava, Ruchi, Spencer, Doran, Garg, Sumit, Fremgen, Daniel, Vahed, Hawa, Lopes, Patricia P., Pham, Thanh T., Hewett, Charlie, Kuang, Jasmine, Ong, Nicolas, Huang, Lei, Scarfone, Vanessa M., Nesburn, Anthony B., Wechsler, Steven L., BenMohamed, Lbachir
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403403/
https://ncbi.nlm.nih.gov/pubmed/25609800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03419-14
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