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Influenza Viruses with Receptor-Binding N1 Neuraminidases Occur Sporadically in Several Lineages and Show No Attenuation in Cell Culture or Mice

In nearly all characterized influenza viruses, hemagglutinin (HA) is the receptor-binding protein while neuraminidase (NA) is a receptor-cleaving protein that aids in viral release. However, in recent years, several groups have described point mutations that confer receptor-binding activity on NA, a...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hooper, Kathryn A., Crowe, James E., Bloom, Jesse D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403400/
https://ncbi.nlm.nih.gov/pubmed/25609803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00012-15
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