Human Immunodeficiency Virus Type 1 Employs the Cellular Dynein Light Chain 1 Protein for Reverse Transcription through Interaction with Its Integrase Protein

In this study, we examined the requirement for host dynein adapter proteins such as dynein light chain 1 (DYNLL1), dynein light chain Tctex-type 1 (DYNLT1), and p150(Glued) in early steps of human immunodeficiency virus type 1 (HIV-1) replication. We found that the knockdown (KD) of DYNLL1, but not...

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Vydáno v:J Virol
Hlavní autoři: Jayappa, Kallesh Danappa, Ao, Zhujun, Wang, Xiaoxia, Mouland, Andrew J., Shekhar, Sudhanshu, Yang, Xi, Yao, Xiaojian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403391/
https://ncbi.nlm.nih.gov/pubmed/25568209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03347-14
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