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Regulation of early T-lineage gene expression and developmental progression by the progenitor cell transcription factor PU.1
The ETS family transcription factor PU.1 is essential for the development of several blood lineages, including T cells, but its function in intrathymic T-cell precursors has been poorly defined. In the thymus, high PU.1 expression persists through multiple cell divisions in early stages but then fal...
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| Udgivet i: | Genes Dev |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4403259/ https://ncbi.nlm.nih.gov/pubmed/25846797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.259879.115 |
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