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Identifying overlapping mutated driver pathways by constructing gene networks in cancer

BACKGROUND: Large-scale cancer genomic projects are providing lots of data on genomic, epigenomic and gene expression aberrations in many cancer types. One key challenge is to detect functional driver pathways and to filter out nonfunctional passenger genes in cancer genomics. Vandin et al. introduc...

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Bibliografische gegevens
Gepubliceerd in:BMC Bioinformatics
Hoofdauteurs: Wu, Hao, Gao, Lin, Li, Feng, Song, Fei, Yang, Xiaofei, Kasabov, Nikola
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402595/
https://ncbi.nlm.nih.gov/pubmed/25859819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S5-S3
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