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Identifying overlapping mutated driver pathways by constructing gene networks in cancer

BACKGROUND: Large-scale cancer genomic projects are providing lots of data on genomic, epigenomic and gene expression aberrations in many cancer types. One key challenge is to detect functional driver pathways and to filter out nonfunctional passenger genes in cancer genomics. Vandin et al. introduc...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Wu, Hao, Gao, Lin, Li, Feng, Song, Fei, Yang, Xiaofei, Kasabov, Nikola
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402595/
https://ncbi.nlm.nih.gov/pubmed/25859819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S5-S3
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