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Identifying overlapping mutated driver pathways by constructing gene networks in cancer
BACKGROUND: Large-scale cancer genomic projects are providing lots of data on genomic, epigenomic and gene expression aberrations in many cancer types. One key challenge is to detect functional driver pathways and to filter out nonfunctional passenger genes in cancer genomics. Vandin et al. introduc...
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| Publié dans: | BMC Bioinformatics |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4402595/ https://ncbi.nlm.nih.gov/pubmed/25859819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S5-S3 |
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