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Identifying overlapping mutated driver pathways by constructing gene networks in cancer

BACKGROUND: Large-scale cancer genomic projects are providing lots of data on genomic, epigenomic and gene expression aberrations in many cancer types. One key challenge is to detect functional driver pathways and to filter out nonfunctional passenger genes in cancer genomics. Vandin et al. introduc...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Wu, Hao, Gao, Lin, Li, Feng, Song, Fei, Yang, Xiaofei, Kasabov, Nikola
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402595/
https://ncbi.nlm.nih.gov/pubmed/25859819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S5-S3
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