DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation

Initiation is a highly regulated rate-limiting step of mRNA translation. During cap-dependent translation, the cap-binding protein eIF4E recruits the mRNA to the ribosome. Specific elements in the 5′UTR of some mRNAs referred to as Internal Ribosome Entry Sites (IRESes) allow direct association of t...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Liberman, Noa, Gandin, Valentina, Svitkin, Yuri V., David, Maya, Virgili, Geneviève, Jaramillo, Maritza, Holcik, Martin, Nagar, Bhushan, Kimchi, Adi, Sonenberg, Nahum
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402527/
https://ncbi.nlm.nih.gov/pubmed/25779044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv205
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