Structural analysis of the DAP5 MIF4G domain and its interaction with eIF4A

Death-associated protein 5 (DAP5/p97) is a homolog of the eukaryotic initiation factor 4G (eIF4G) that promotes the IRES-driven translation of multiple cellular mRNAs. Central to its function is the middle domain (MIF4G), which recruits the RNA helicase eIF4A. The middle domain of eIF4G consists of...

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Huvudupphovsmän: Virgili, Geneviève, Frank, Filipp, Feoktistova, Kateryna, Sawicki, Maxime, Sonenberg, Nahum, Fraser, Christopher S., Nagar, Bhushan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659266/
https://ncbi.nlm.nih.gov/pubmed/23478064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.01.015
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