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Crystal structure of Hop2–Mnd1 and mechanistic insights into its role in meiotic recombination
In meiotic DNA recombination, the Hop2−Mnd1 complex promotes Dmc1-mediated single-stranded DNA (ssDNA) invasion into homologous chromosomes to form a synaptic complex by a yet-unclear mechanism. Here, the crystal structure of Hop2−Mnd1 reveals that it forms a curved rod-like structure consisting of...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4402518/ https://ncbi.nlm.nih.gov/pubmed/25740648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv172 |
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