H(2)S mitigates severe acute pancreatitis through the PI(3)K/AKT-NF-κB pathway in vivo

AIM: To study the effect of hydrogen sulfide (H(2)S) on severe acute pancreatitis (SAP) in a rat model. METHODS: Sprague-Dawley (SD) rats were administered an intraperitoneal injection of saline containing 20% L-Arg (250 mg/100 g) hourly for over 2 h to induce SAP. The rats were treated with DL-prop...

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Bibliographic Details
Published in:World J Gastroenterol
Main Authors: Rao, Chun-Yan, Fu, Lan-Ying, Hu, Chang-Lun, Chen, Dai-Xing, Gan, Tian, Wang, Yi-Cheng, Zhao, Xiao-Yan
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Inc 2015
Subjects:
Basic Study
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402302/
https://ncbi.nlm.nih.gov/pubmed/25914464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i15.4555
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