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Irisin Enhances Doxorubicin-Induced Cell Apoptosis in Pancreatic Cancer by Inhibiting the PI3K/AKT/NF-κB Pathway

BACKGROUND: Irisin, a myokine released from skeletal muscle following exercise, has been shown to affect the proliferation of some cancer cells and chemosensitivity of anticancer drugs like doxorubicin (DOX). However, the effects of irisin on chemosensitivity in pancreatic cancer (PC) cells have not...

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Библиографические подробности
Опубликовано в: :Med Sci Monit
Главные авторы: Liu, Jiayu, Huang, Yibing, Liu, Yu, Chen, Yuxin
Формат: Artigo
Язык:Inglês
Опубликовано: International Scientific Literature, Inc. 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705179/
https://ncbi.nlm.nih.gov/pubmed/31412018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.917625
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