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Irisin Enhances Doxorubicin-Induced Cell Apoptosis in Pancreatic Cancer by Inhibiting the PI3K/AKT/NF-κB Pathway

BACKGROUND: Irisin, a myokine released from skeletal muscle following exercise, has been shown to affect the proliferation of some cancer cells and chemosensitivity of anticancer drugs like doxorubicin (DOX). However, the effects of irisin on chemosensitivity in pancreatic cancer (PC) cells have not...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Med Sci Monit
Main Authors: Liu, Jiayu, Huang, Yibing, Liu, Yu, Chen, Yuxin
Format: Artigo
Jezik:Inglês
Izdano: International Scientific Literature, Inc. 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705179/
https://ncbi.nlm.nih.gov/pubmed/31412018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.917625
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