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Irisin Enhances Doxorubicin-Induced Cell Apoptosis in Pancreatic Cancer by Inhibiting the PI3K/AKT/NF-κB Pathway

BACKGROUND: Irisin, a myokine released from skeletal muscle following exercise, has been shown to affect the proliferation of some cancer cells and chemosensitivity of anticancer drugs like doxorubicin (DOX). However, the effects of irisin on chemosensitivity in pancreatic cancer (PC) cells have not...

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Vydáno v:Med Sci Monit
Hlavní autoři: Liu, Jiayu, Huang, Yibing, Liu, Yu, Chen, Yuxin
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705179/
https://ncbi.nlm.nih.gov/pubmed/31412018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.917625
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