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Methotrexate modulates folate phenotype and inflammatory profile in EA.hy 926 cells

EA.hy 926 cells grown under low folate conditions adopt a “pro-atherosclerotic” morphology and biochemical phenotype. Pharmacologically relevant doses of the antifolate drug methotrexate (MTX) were applied to EA.hy 926 cells maintained in normal (Hi) and low (Lo) folate culture media. Under both fol...

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Publicado en:Eur J Pharmacol
Autores principales: Summers, Carolyn M., Hammons, Andrea L., Arora, Jasbir, Zhang, Suhong, Jochems, Jeanine, Blair, Ian A., Whitehead, Alexander S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402228/
https://ncbi.nlm.nih.gov/pubmed/24657277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2014.03.004
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