Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation

Stimulation of the aryl hydrocarbon receptor (AHR) by xenobiotics is known to affect epidermal differentiation and skin barrier formation. The physiological role of endogenous AHR signaling in keratinocyte differentiation is not known. We used murine and human skin models to address the hypothesis t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Invest Dermatol
Prif Awduron: van den Bogaard, Ellen, Podolsky, Michael, Smits, Jos, Cui, Xiao, John, Christian, Gowda, Krishne, Desai, Dhimant, Amin, Shantu, Schalkwijk, Joost, Perdew, Gary H., Glick, Adam B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402116/
https://ncbi.nlm.nih.gov/pubmed/25602157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.6
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg