Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation

Stimulation of the aryl hydrocarbon receptor (AHR) by xenobiotics is known to affect epidermal differentiation and skin barrier formation. The physiological role of endogenous AHR signaling in keratinocyte differentiation is not known. We used murine and human skin models to address the hypothesis t...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: van den Bogaard, Ellen, Podolsky, Michael, Smits, Jos, Cui, Xiao, John, Christian, Gowda, Krishne, Desai, Dhimant, Amin, Shantu, Schalkwijk, Joost, Perdew, Gary H., Glick, Adam B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402116/
https://ncbi.nlm.nih.gov/pubmed/25602157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.6
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