Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation

Stimulation of the aryl hydrocarbon receptor (AHR) by xenobiotics is known to affect epidermal differentiation and skin barrier formation. The physiological role of endogenous AHR signaling in keratinocyte differentiation is not known. We used murine and human skin models to address the hypothesis t...

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Détails bibliographiques
Publié dans:J Invest Dermatol
Auteurs principaux: van den Bogaard, Ellen, Podolsky, Michael, Smits, Jos, Cui, Xiao, John, Christian, Gowda, Krishne, Desai, Dhimant, Amin, Shantu, Schalkwijk, Joost, Perdew, Gary H., Glick, Adam B.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402116/
https://ncbi.nlm.nih.gov/pubmed/25602157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.6
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