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The Normal and Pathologic Roles of the Alzheimer's β-secretase, BACE1

As the most common neurodegenerative disease, therapeutic avenues for the treatment and prevention of Alzheimer's Disease are highly sought after. The aspartic protease BACE1 is the initiator enzyme for the formation of Aβ, a major constituent of amyloid plaques that represent one of the hallma...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Curr Alzheimer Res
Main Authors: Kandalepas, Patty C., Vassar, Robert
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401991/
https://ncbi.nlm.nih.gov/pubmed/24893886
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