Preclinical Studies in Support of Defibrotide for the Treatment of Multiple Myeloma and Other Neoplasias

PURPOSE OF THE STUDY: Defibrotide (DF), an orally bioavailable polydisperse oligonucleotide has promising activity in hepatic veno-occlusive disease (VOD), a stem cell transplantation-related toxicity, characterized by microangiopathy. The anti-thrombotic properties of DF and its minimal hemorrhagic...

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Gepubliceerd in:Clin Cancer Res
Hoofdauteurs: Mitsiades, Constantine S., Rouleau, Cecile, Echart, Cinara, Menon, Krishna, Teicher, Beverly, Distaso, Maria, Palumbo, Antonio, Boccadoro, Mario, Anderson, Kenneth C., Iacobelli, Massimo, Richardson, Paul G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401498/
https://ncbi.nlm.nih.gov/pubmed/19228727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1270
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