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Functional Characterization of Na(+)/H(+) Exchangers of Intracellular Compartments Using Proton-killing Selection to Express Them at the Plasma Membrane
Endosomal acidification is critical for a wide range of processes, such as protein recycling and degradation, receptor desensitization, and neurotransmitter loading in synaptic vesicles. This acidification is described to be mediated by proton ATPases, coupled to ClC chloride transporters. Highly-co...
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| Publicado no: | J Vis Exp |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MyJove Corporation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4401382/ https://ncbi.nlm.nih.gov/pubmed/25867523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52453 |
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