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Functional Characterization of Na(+)/H(+) Exchangers of Intracellular Compartments Using Proton-killing Selection to Express Them at the Plasma Membrane

Endosomal acidification is critical for a wide range of processes, such as protein recycling and degradation, receptor desensitization, and neurotransmitter loading in synaptic vesicles. This acidification is described to be mediated by proton ATPases, coupled to ClC chloride transporters. Highly-co...

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書目詳細資料
發表在:J Vis Exp
Main Authors: Milosavljevic, Nina, Poët, Mallorie, Monet, Michael, Birgy-Barelli, Eléonore, Léna, Isabelle, Counillon, Laurent
格式: Artigo
語言:Inglês
出版: MyJove Corporation 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401382/
https://ncbi.nlm.nih.gov/pubmed/25867523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52453
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