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Endoplasmic Reticulum Stress–Induced IRE1α Activation Mediates Cross-Talk of GSK-3β and XBP-1 To Regulate Inflammatory Cytokine Production

IL-1β and TNF-α are important proinflammatory cytokines that respond to mutated self-antigens of tissue damage and exogenous pathogens. The endoplasmic reticulum (ER) stress and unfolded protein responses are related to the induction of proinflammatory cytokines. However, the detailed molecular path...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Kim, Sena, Joe, Yeonsoo, Kim, Hyo Jeong, Kim, You-Sun, Jeong, Sun Oh, Pae, Hyun-Ock, Ryter, Stefan W., Surh, Young-Joon, Chung, Hun Taeg
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400814/
https://ncbi.nlm.nih.gov/pubmed/25821218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401399
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