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Inhibiting the inflammasome: one domain at a time

Inflammasomes are protein complexes that promote the maturation and release of pro-inflammatory cytokines and danger signals as well as pyroptosis in response to infections and cellular stress. Inflammasomes consist of a sensor, an adapter, and the effector caspase-1, which interact through homotypi...

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Detalhes bibliográficos
Publicado no:Immunol Rev
Main Authors: Dorfleutner, Andrea, Chu, Lan, Stehlik, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400809/
https://ncbi.nlm.nih.gov/pubmed/25879295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12290
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