KLF4 N-Terminal Variance Modulates Induced Reprogramming to Pluripotency

As the quintessential reprogramming model, OCT3/4, SOX2, KLF4, and c-MYC re-wire somatic cells to achieve induced pluripotency. Yet, subtle differences in methodology confound comparative studies of reprogramming mechanisms. Employing transposons, we systematically assessed cellular and molecular ha...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Kim, Shin-Il, Oceguera-Yanez, Fabian, Hirohata, Ryoko, Linker, Sara, Okita, Keisuke, Yamada, Yasuhiro, Yamamoto, Takuya, Yamanaka, Shinya, Woltjen, Knut
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400650/
https://ncbi.nlm.nih.gov/pubmed/25772473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.02.004
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