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Increased expression of renal TRPM6 compensates for Mg(2+) wasting during furosemide treatment
BACKGROUND: Furosemide is a loop diuretic, which blocks the Na(+), K(+), 2Cl(−) cotransporter (NKCC2) in the thick ascending limb of Henle (TAL). By diminishing sodium (Na(+)) reabsorption, loop diuretics reduce the lumen-positive transepithelial voltage and consequently diminish paracellular transp...
में बचाया:
में प्रकाशित: | Clin Kidney J |
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मुख्य लेखकों: | , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Oxford University Press
2012
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4400563/ https://ncbi.nlm.nih.gov/pubmed/26069797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ckj/sfs140 |
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