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Increased expression of renal TRPM6 compensates for Mg(2+) wasting during furosemide treatment
BACKGROUND: Furosemide is a loop diuretic, which blocks the Na(+), K(+), 2Cl(−) cotransporter (NKCC2) in the thick ascending limb of Henle (TAL). By diminishing sodium (Na(+)) reabsorption, loop diuretics reduce the lumen-positive transepithelial voltage and consequently diminish paracellular transp...
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| Publicado no: | Clin Kidney J |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4400563/ https://ncbi.nlm.nih.gov/pubmed/26069797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ckj/sfs140 |
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