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EGF Increases TRPM6 Activity and Surface Expression

Recent identification of a mutation in the EGF gene that causes isolated recessive hypomagnesemia led to the finding that EGF increases the activity of the epithelial magnesium (Mg(2+)) channel transient receptor potential M6 (TRPM6). To investigate the molecular mechanism mediating this effect, we...

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Detalhes bibliográficos
Main Authors: Thebault, Stéphanie, Alexander, R. Todd, Tiel Groenestege, Wouter M., Hoenderop, Joost G., Bindels, René J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615736/
https://ncbi.nlm.nih.gov/pubmed/19073827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008030327
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