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Intracellular Trafficking of Plasmids for Gene Therapy: Mechanisms of Cytoplasmic Movement and Nuclear Import

Under physiologically relevant conditions, the levels of non-viral gene transfer are low at best. The reason for this is that many barriers exist for the efficient transfer of genes to cells, even before any gene expression can occur. While many transfection strategies focus on DNA condensation and...

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Detalhes bibliográficos
Publicado no:Curr Gene Ther
Principais autores: Vaughan, Erin E., DeGiulio, James V., Dean, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400175/
https://ncbi.nlm.nih.gov/pubmed/17168698
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