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Intracellular trafficking of plasmids during transfection is mediated by microtubules

Little is known about how plasmids move through the cytoplasm to the nucleus. It has been suggested that the dense latticework of the cytoskeleton impedes free diffusion of large macromolecules, including DNA. However, since transfections do work, there must be mechanisms by which DNA circumvents cy...

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Detalhes bibliográficos
Main Authors: Vaughan, Erin E., Dean, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150869/
https://ncbi.nlm.nih.gov/pubmed/16301002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2005.10.004
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