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Intracellular trafficking of plasmids during transfection is mediated by microtubules

Little is known about how plasmids move through the cytoplasm to the nucleus. It has been suggested that the dense latticework of the cytoskeleton impedes free diffusion of large macromolecules, including DNA. However, since transfections do work, there must be mechanisms by which DNA circumvents cy...

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Autors principals: Vaughan, Erin E., Dean, David A.
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150869/
https://ncbi.nlm.nih.gov/pubmed/16301002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2005.10.004
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