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Intracellular trafficking of plasmids during transfection is mediated by microtubules

Little is known about how plasmids move through the cytoplasm to the nucleus. It has been suggested that the dense latticework of the cytoskeleton impedes free diffusion of large macromolecules, including DNA. However, since transfections do work, there must be mechanisms by which DNA circumvents cy...

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Dettagli Bibliografici
Autori principali: Vaughan, Erin E., Dean, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150869/
https://ncbi.nlm.nih.gov/pubmed/16301002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2005.10.004
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