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Affinity-Based Assays for the Identification and Quantitative Evaluation of Noncovalent Poly(ADP-Ribose)-Binding Proteins

Poly(ADP-ribose) polymerases have been linked to several cellular functions, most of which being mediated through the dynamics of poly(ADP-ribose) (pADPr). In several pathways, pADPr is the effector molecule that regulates cellular signaling and dictates biological outcomes. pAPDr is a central molec...

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Bibliographische Detailangaben
Veröffentlicht in:Methods Mol Biol
Hauptverfasser: Gagné, Jean-Philippe, Haince, Jean-François, Pic, Émilie, Poirier, Guy G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399804/
https://ncbi.nlm.nih.gov/pubmed/21870257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-270-0_7
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