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Crystallographic and Biochemical Analysis of the Mouse Poly(ADP-Ribose) Glycohydrolase
Protein poly(ADP-ribosyl)ation (PARylation) regulates a number of important cellular processes. Poly(ADP-ribose) glycohydrolase (PARG) is the primary enzyme responsible for hydrolyzing the poly(ADP-ribose) (PAR) polymer in vivo. Here we report crystal structures of the mouse PARG (mPARG) catalytic d...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3897571/ https://ncbi.nlm.nih.gov/pubmed/24465839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086010 |
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