Quantitative proteomics profiling of the poly(ADP-ribose)-related response to genotoxic stress

Upon DNA damage induction, DNA-dependent poly(ADP-ribose) polymerases (PARPs) synthesize an anionic poly(ADP-ribose) (pADPr) scaffold to which several proteins bind with the subsequent formation of pADPr-associated multiprotein complexes. We have used a combination of affinity-purification methods a...

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Bibliografiska uppgifter
Huvudupphovsmän: Gagné, Jean-Philippe, Pic, Émilie, Isabelle, Maxim, Krietsch, Jana, Éthier, Chantal, Paquet, Éric, Kelly, Isabelle, Boutin, Michel, Moon, Kyung-Mee, Foster, Leonard J., Poirier, Guy G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2012
Ämnen:
Genome Integrity, Repair and Replication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439892/
https://ncbi.nlm.nih.gov/pubmed/22669911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks486
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