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Quantitative proteomics profiling of the poly(ADP-ribose)-related response to genotoxic stress
Upon DNA damage induction, DNA-dependent poly(ADP-ribose) polymerases (PARPs) synthesize an anionic poly(ADP-ribose) (pADPr) scaffold to which several proteins bind with the subsequent formation of pADPr-associated multiprotein complexes. We have used a combination of affinity-purification methods a...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3439892/ https://ncbi.nlm.nih.gov/pubmed/22669911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks486 |
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