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Dynamics of B cells in germinal centres

Humoral immunity depends on the germinal centre (GC) reaction during which somatically mutated high-affinity memory B cells and plasma cells are generated. Recent studies have uncovered crucial cues that are required for the formation and the maintenance of GCs and for the selection of high-affinity...

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Détails bibliographiques
Publié dans:Nat Rev Immunol
Auteurs principaux: De Silva, Nilushi S., Klein, Ulf
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399774/
https://ncbi.nlm.nih.gov/pubmed/25656706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3804
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