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Dynamics of B cells in germinal centres
Humoral immunity depends on the germinal centre (GC) reaction during which somatically mutated high-affinity memory B cells and plasma cells are generated. Recent studies have uncovered crucial cues that are required for the formation and the maintenance of GCs and for the selection of high-affinity...
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| Veröffentlicht in: | Nat Rev Immunol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4399774/ https://ncbi.nlm.nih.gov/pubmed/25656706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3804 |
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