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Transcription factors of the alternative NF-κB pathway are required for germinal center B-cell development

The NF-κB signaling cascade relays external signals essential for B-cell growth and survival. This cascade is frequently hijacked by cancers that arise from the malignant transformation of germinal center (GC) B cells, underscoring the importance of deciphering the function of NF-κB in these cells....

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: De Silva, Nilushi S., Anderson, Michael M., Carette, Amanda, Silva, Kathryn, Heise, Nicole, Bhagat, Govind, Klein, Ulf
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987794/
https://ncbi.nlm.nih.gov/pubmed/27457956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602728113
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