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Pelvic irradiation modulates the pharmacokinetics of cisplatin in the plasma and lymphatic system

Background: Cisplatin (CDDP) is employed to enhance radiotherapy’s (RT) effect for various cancers. However, the effects of local RT on chemotherapeutics in the plasma and lymphatic system remain unclear. Here, we evaluated the influence of pelvic irradiation on the pharmacokinetics (PK) of CDDP usi...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Transl Res
Hauptverfasser: Tsai, Tung-Hu, Chen, Yu-Jen, Hou, Mei-Ling, Wang, Li-Ying, Tai, Hung-Chi, Hsieh, Chen-Hsi
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399100/
https://ncbi.nlm.nih.gov/pubmed/25901204
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