Induction of Caspase-11 by Aspartyl Proteinases of Candida albicans and Implication in Promoting Inflammatory Response

We recently demonstrated that the secreted aspartyl proteinases (Saps), Sap2 and Sap6, of Candida albicans have the potential to induce the canonical activation of the NLRP3 inflammasome, leading to the secretion of interleukin-1β (IL-1β) and IL-18 via caspase-1 activation. We also observed that the...

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Dades bibliogràfiques
Publicat a:Infect Immun
Autors principals: Gabrielli, Elena, Pericolini, Eva, Luciano, Eugenio, Sabbatini, Samuele, Roselletti, Elena, Perito, Stefano, Kasper, Lydia, Hube, Bernhard, Vecchiarelli, Anna
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Host Response and Inflammation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399077/
https://ncbi.nlm.nih.gov/pubmed/25712931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02895-14
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