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miR-1269 Promotes Metastasis and Forms a Positive Feedback Loop with TGF-β

As patient survival drops precipitously from early-stage cancers to late-stage and metastatic cancers, microRNAs that promote relapse and metastasis can serve as prognostic and predictive markers as well as therapeutic targets for chemoprevention. Here we show that miR-1269a promotes colorectal canc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Bu, Pengcheng, Wang, Lihua, Chen, Kai-Yuan, Rakhilin, Nikolai, Sun, Jian, Closa, Adria, Tung, Kuei-Ling, King, Sarah, Varanko, Anastasia Kristine, Xu, Yitian, Chen, Joyce Huan, Zessin, Amelia S, Shealy, James, Cummings, Bethany, Hsu, David, Lipkin, Steven M., Moreno, Victor, Gümüş, Zeynep H., Shen, Xiling
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399006/
https://ncbi.nlm.nih.gov/pubmed/25872451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7879
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