Increased prevalence of EPAS1 variant in cattle with high-altitude pulmonary hypertension

High-altitude pulmonary hypertension (HAPH) has heritable features and is a major cause of death in cattle in the Rocky Mountains, USA. Although multiple genes are likely involved in the genesis of HAPH, to date no major gene variant has been identified. Using whole-exome sequencing, we report the h...

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Publicado en:Nat Commun
Autores principales: Newman, John H., Holt, Timothy N., Cogan, Joy D., Womack, Bethany, Phillips, John A., Li, Chun, Kendall, Zachary, Stenmark, Kurt R., Thomas, Milton G., Brown, R. Dale, Riddle, Suzette R., West, James D., Hamid, Rizwan
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399003/
https://ncbi.nlm.nih.gov/pubmed/25873470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7863
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