Increased prevalence of EPAS1 variant in cattle with high-altitude pulmonary hypertension

High-altitude pulmonary hypertension (HAPH) has heritable features and is a major cause of death in cattle in the Rocky Mountains, USA. Although multiple genes are likely involved in the genesis of HAPH, to date no major gene variant has been identified. Using whole-exome sequencing, we report the h...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Newman, John H., Holt, Timothy N., Cogan, Joy D., Womack, Bethany, Phillips, John A., Li, Chun, Kendall, Zachary, Stenmark, Kurt R., Thomas, Milton G., Brown, R. Dale, Riddle, Suzette R., West, James D., Hamid, Rizwan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399003/
https://ncbi.nlm.nih.gov/pubmed/25873470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7863
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