Increased prevalence of EPAS1 variant in cattle with high-altitude pulmonary hypertension

High-altitude pulmonary hypertension (HAPH) has heritable features and is a major cause of death in cattle in the Rocky Mountains, USA. Although multiple genes are likely involved in the genesis of HAPH, to date no major gene variant has been identified. Using whole-exome sequencing, we report the h...

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Udgivet i:Nat Commun
Main Authors: Newman, John H., Holt, Timothy N., Cogan, Joy D., Womack, Bethany, Phillips, John A., Li, Chun, Kendall, Zachary, Stenmark, Kurt R., Thomas, Milton G., Brown, R. Dale, Riddle, Suzette R., West, James D., Hamid, Rizwan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399003/
https://ncbi.nlm.nih.gov/pubmed/25873470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7863
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