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Bicarbonate conductance and pH regulatory capability of cystic fibrosis transmembrane conductance regulator.

The cystic fibrosis transmembrane conductance regulator (CFTR) is an epithelial Cl- channel regulated by protein kinase A. The most common mutation in cystic fibrosis (CF), deletion of Phe-508 (delta F508-CFTR), reduces Cl- secretion, but the fatal consequences of CF have been difficult to rationali...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Poulsen, J H, Fischer, H, Illek, B, Machen, T E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43990/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7515498/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.12.5340
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